![]() The hypothesis of the psychosis continuum enables to study the mechanisms of psychosis risk not only in clinical samples but in non-clinical as well. Overall, the current study indicates that subgroups in the CHR population with a higher risk of non-remission or deterioration may be identified by supplementing CHR criteria with assessment of BSD and negative symptoms. Increased BSD levels were associated with higher baseline BSD levels, non-remission of positive symptoms and functional decline. Mean BSD levels decreased significantly from baseline to follow-up, but individual trajectories varied considerably. We found higher BSD levels at follow-up in subjects with schizotypal personality disorder (SPD) at baseline ( n = 5) and in SSDs at follow-up ( n = 12, including nine with SPD). All measured at follow-up, higher BSD levels correlated with higher severity of positive, negative, disorganization and general symptoms, and with a lower level of global functioning. Higher severity of negative symptoms and meeting COGDIS criteria at baseline were associated with higher BSD levels at follow-up. DSM-IV diagnoses, functioning and other clinical characteristics were assessed with standard clinical instruments. Clinical high risk (CHR) for psychosis status and symptom severity were assessed with the SIPS/SOPS scales and also according to the cognitive basic symptoms high-risk criteria (COGDIS). In a one-year follow-up of 32 patients (15–30 years) at putative risk for psychosis, we investigated trajectories of BSD levels from baseline to follow-up, and associations between clinical characteristics at baseline and follow-up, including follow-up levels of BSD (assessed with the EASE). The features may additionally represent precursors of psychosis transition, useful for clinical decision-making.įoundation Dam, Oslo, Norway (Grant Number 2017/FO143368)īasic self-disturbance (BSD) has been proposed as a driver of symptom development in schizophrenia spectrum disorders (SSDs). This unique irregular “BSD -language” was highly meaningful in its proper context, expressing informative characteristics of first-personal experiential alterations, essential for early detection. The adolescents provided naturalistic descriptions of experiences that were markedly twisted and almost ineffable. We identified five clusters of irregular language features: distinctive words, describing an atmosphere of unreality irregular use of prepositions, indicating experiential detachment shifts of personal pronouns, indicating identity confusion near-literal use of metaphors and conjunctions indicating existential insecurity, and idiosyncratic use of adjectives indicating perceptual transcendence. Ninety verbatim statements were analyzed and grouped into higher order clusters of linguistic irregularities. Participants chose three personal and well manifested BSD phenomena. Standard instruments established psychosis risk and BSD. ![]() We searched for distinctive irregular linguistics of 30 CHR outpatient adolescents, aged 12–18 years. Recent phenomenologic-psychiatric studies claim that basic self-disturbance (BSD) may represent more useful early markers. Incoherence, derailment, and monotonous speaking are however closely related to psychosis onset, and thus not very early markers. Language impairments are key features of schizophrenia spectrum disorders, and have also been suggested to signal enhanced psychosis risk.
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